血管音图检查：一种用于研究动脉疾病的新型非侵入性诊断方法。
Phonoangiography: a new noninvasive diagnostic method for studying arterial disease.
作者信息
Lees R S, Dewey C F
出版信息
Proc Natl Acad Sci U S A. 1970 Oct;67(2):935-42. doi: 10.1073/pnas.67.2.935.
Abstract
Phonoangiography, the quantitative analysis of sounds produced by blood flow, has been used to investigate local fluid motion in arteries narrowed by atherosclerosis. The sound spectra measured in vivo were found to be identical to those obtained in laboratory investigations of turbulent pipe flow. A theoretical model is proposed which: (a) quantitatively relates the in vivo and in vitro data, and (b) allows estimation of the clinically important parameters of arterial diameter, flow velocity, local turbulence intensity, and wall pressure fluctuations. The results of calculations using data from human subjects agree with known arterial diameters and blood flow velocities.
摘要
血管音图法，即对血流产生的声音进行定量分析，已被用于研究动脉粥样硬化导致狭窄的动脉中的局部流体运动。在体内测量的声谱被发现与在实验室对紊流管道流动的研究中获得的声谱相同。提出了一个理论模型，该模型：(a) 定量关联体内和体外数据，以及 (b) 允许估计动脉直径、流速、局部湍流强度和壁面压力波动等临床重要参数。使用来自人类受试者的数据进行计算的结果与已知的动脉直径和血流速度相符。
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Proc Natl Acad Sci U S A. 1970 Oct;67(2):935-42. doi: 10.1073/pnas.67.2.935.
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