Schenck H U, Simak P, Haedicke E
J Pharm Sci. 1979 Dec;68(12):1505-9. doi: 10.1002/jps.2600681211.
Hydrogen triiodide adducts were prepared from N,N-dimethylacetamide, N-alkylpyrrolidone derivatives, and polyvinylpyrrolidone, and their structures were investigated by IR spectra and X-ray structure analyses and compared with the structure of povidone-iodine USP. The results suggest that the iodine in povidone-iodine USP is complexed by the polymer such that a proton is fixed via a short hydrogen bond between two carbonyl groups of two pyrrolidone rings and that a triiodide anion is bound ionically to this cation.
三碘化氢加合物由N,N-二甲基乙酰胺、N-烷基吡咯烷酮衍生物和聚乙烯吡咯烷酮制备而成，通过红外光谱和X射线结构分析对其结构进行了研究，并与美国药典聚维酮碘的结构进行了比较。结果表明，美国药典聚维酮碘中的碘与聚合物形成络合物，使得一个质子通过两个吡咯烷酮环的两个羰基之间的短氢键固定，并且一个三碘阴离子以离子键形式与该阳离子结合。
