Davis A
Bull World Health Organ. 1966;35(6):827-35.
The deficiencies of the drugs used for the treatment of bilharziasis have limited attempts at control of the disease by chemotherapy. The present paper records a series of field trials with a new, orally administered, non-metallic schistosomicide, Ambilhar, in schoolchildren in an area of endemic urinary bilharziasis in Tanzania. The results indicate that the compound represents an important advance in the chemotherapy of Schistosoma haematobium infections. High cure rates and marked reduction of egg excretion in those not cured reveal prospects of wider population coverage by drug treatment of schoolchildren, the age-group most at risk and most in need of treatment.
用于治疗血吸虫病的药物存在缺陷，这限制了通过化疗控制该疾病的尝试。本文记录了在坦桑尼亚泌尿血吸虫病流行地区对学童使用一种新型口服非金属杀血吸虫药——氨比哈（Ambilhar）进行的一系列现场试验。结果表明，该化合物在埃及血吸虫感染的化疗方面代表了一项重要进展。高治愈率以及未治愈者虫卵排泄量的显著减少，揭示了通过对学童（最易感染且最需要治疗的年龄组）进行药物治疗来扩大人群覆盖范围的前景。
