Gresíková M, Kozuch O, Molnár E
Bull World Health Organ. 1967;36 Suppl(Suppl 1):81-4.
The isolation of tick-borne encephalitis (TBE) virus from the spinal fluid of a patient with a clinical diagnosis of meningo-encephalitis and the demonstration of virus-neutralizing antibodies in sera from inhabitants of the Tribec region have shown this area to be an active natural focus of tick-borne encephalitis. Of healthy people from the villages of Jarok and Kostolany, 26% had antibodies to TBE virus. Children from Kostolany had no such antibodies, whereas in Jarok 7% of children less than 15 years old were serologically positive. This finding, together with the generally higher antibody titres of sera from inhabitants of Jarok, suggests that this elementary focus of tick-borne encephalitis has been active more recently than that in Kostolany. In both villages the frequency of antibodies was high in persons over 55 years old (50% in Jarok and 63% in Kostolany); the highest frequency was found in those working regularly within the natural focus, i.e., forest workers and housewives.
从一名临床诊断为脑膜脑炎患者的脑脊液中分离出蜱传脑炎（TBE）病毒，并且在特里贝克地区居民的血清中检测到病毒中和抗体，这表明该地区是蜱传脑炎的一个活跃自然疫源地。来自亚罗克村和科斯托拉尼村的健康人群中，26%的人具有抗TBE病毒抗体。科斯托拉尼村的儿童没有此类抗体，而在亚罗克村，15岁以下儿童中有7%血清学检测呈阳性。这一发现，再加上亚罗克村居民血清中抗体滴度总体较高，表明这个蜱传脑炎基本疫源地比科斯托拉尼村的疫源地近期更为活跃。在两个村庄中，55岁以上人群的抗体频率都很高（亚罗克村为50%，科斯托拉尼村为63%）；抗体频率最高的是那些经常在自然疫源地内工作的人，即森林工人和家庭主妇。
