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[吉兰-巴雷综合征与B型急性肝炎相关(作者译)]

[Guillain-Barré syndrome associated to a type B acute hepatitis (author's transl)].

作者信息

Martí-Massó J F, Obeso J A, Cosme A, de la Fuente E, Carrera N, Figols J

出版信息

Med Clin (Barc). 1979 Dec 15;73(10):447-50.

PMID:529867
Abstract

A 42-year-old male patient suffers an acute hepatitis with positive HBs Ag and approximately 2 months after its onset, an acute polyneuritis with lessening of conduction velocity and albumino-cytologic dissociation appeared. Both conditions recuperated synchronously in a few months. This association has been only slightly referred to previously, and the majority of cases lacked facts important to the establishment of a diagnosis. The polyneuritis is possibly secondary to the viral alteration, either directly or due to an ensuing immunological alteration. Besides, there is the possibility that a clinical or sub-clinical demyelinizing neuropathy that does not fill the criteria of a Guillain-Barré syndrome may complicate a hepatitis, or that an acute polyneuritis may associate itself to an autoimmune hepatitis.

摘要

一名42岁男性患者患急性肝炎,乙肝表面抗原呈阳性,发病约2个月后出现急性多发性神经炎,传导速度减慢,蛋白细胞分离。两种病症在几个月内同步恢复。这种关联此前仅有少量提及,且大多数病例缺乏对确诊至关重要的事实依据。多发性神经炎可能继发于病毒改变,直接原因或继发于随后的免疫改变。此外,有可能不符合吉兰 - 巴雷综合征标准的临床或亚临床脱髓鞘性神经病变会使肝炎复杂化,或者急性多发性神经炎可能与自身免疫性肝炎相关。

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