Salter R H, Read A E
Gut. 1970 Jul;11(7):585-7. doi: 10.1136/gut.11.7.585.
On the supposition that excessive fibrinolysis at the rectal mucosal level may contribute to the pathogenesis of ulcerative colitis, 11 patients with this condition, in whom rectal bleeding was the predominant feature, were given a course of epsilon-aminocaproic acid therapy. Six patients responded dramatically to this treatment, there was a partial response in two, no effect in two others, and one patient found it necessary to discontinue the treatment after 48 hours because of the severity of side effects.
基于直肠黏膜水平过度纤维蛋白溶解可能促成溃疡性结肠炎发病机制的假设，对11例以直肠出血为主要特征的该疾病患者给予了一个疗程的ε-氨基己酸治疗。6例患者对该治疗反应显著，2例部分缓解，另外2例无效，1例患者因副作用严重在48小时后不得不停止治疗。
