Sahud M A, Cohen R J
Calif Med. 1971 Oct;115(4):10-3.
Ivy bleeding time values before and two hours after ingestion of 600 mg of aspirin (aspirin tolerance test) were studied in normal persons, in patients with a disorder of primary hemostasis and in patients with various coagulation factor deficiencies. Aspirin produced a significant prolongation of the bleeding time in patients with von Willebrand's disease, uremia, and primary platelet disease, and in two patients with Factor XI deficiency. Dextropropoxyphene hydrochloride caused no prolongation of the bleeding time in normal persons.
对正常人、原发性止血功能障碍患者以及各种凝血因子缺乏患者,研究了口服600毫克阿司匹林前后(阿司匹林耐量试验)的常春藤出血时间值。阿司匹林使血管性血友病、尿毒症、原发性血小板疾病患者以及两名因子XI缺乏患者的出血时间显著延长。盐酸右丙氧芬未使正常人的出血时间延长。