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三磷酸腺苷对蛙肌电解质水平的代谢协同控制

Metabolic cooperative control of electrolyte levels by adenosine triphosphate in the frog muscle.

作者信息

Gulati J, Ochesenfeld M M, Ling G N

出版信息

Biophys J. 1971 Dec;11(12):973-80. doi: 10.1016/s0006-3495(71)86271-9.

Abstract

This study examines the effects of metabolic inhibitors on the content of cellular K, Na, and adenosine triphosphate (ATP). ATP and K are seen to fall in the inhibited tissues. The ATP content is correlated with the K content. The role of ATP is examined according to a recent biophysical approach. It is suggested that ATP may control the electrolyte levels by inducing conformational changes in the cytoplasmic proteins.

摘要

本研究考察了代谢抑制剂对细胞内钾、钠和三磷酸腺苷(ATP)含量的影响。在受抑制的组织中,ATP和钾含量均下降。ATP含量与钾含量相关。根据最近的生物物理学方法对ATP的作用进行了研究。研究表明,ATP可能通过诱导细胞质蛋白的构象变化来控制电解质水平。

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