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二磷酸甘油酸和肌醇六磷酸对血红蛋白氧结合的控制:实验数据的理论解释

Diphosphoglycerate and inosine hexaphosphate control of oxygen binding by hemoglobin: a theoretical interpretation of experimental data.

作者信息

Ling G N

出版信息

Proc Natl Acad Sci U S A. 1970 Sep;67(1):296-301. doi: 10.1073/pnas.67.1.296.

Abstract

A theoretical equation is presented for the control of cooperative adsorption on proteins and other linear macromolecules by hormones, drugs, ATP, and other "cardinal adsorbents." With reasonable accuracy, this equation describes quantitatively the control of oxygen binding to hemoglobin by 2,3-diphosphoglycerate and by inosine hexaphosphate.

摘要

本文提出了一个理论方程,用于描述激素、药物、三磷酸腺苷(ATP)及其他“主要吸附剂”对蛋白质和其他线性大分子上协同吸附的控制作用。该方程能以合理的准确度定量描述2,3-二磷酸甘油酸酯和肌醇六磷酸对血红蛋白氧结合的控制。

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本文引用的文献

1
ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL.
J Mol Biol. 1965 May;12:88-118. doi: 10.1016/s0022-2836(65)80285-6.
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