敌百虫对家猫彭亨丝虫感染的影响。
The effect of metrifonate on Brugia pahangi infections in domestic cats.
作者信息
Denham D A, Ponnudurai T, Nelson G S, Guy F, Rogers R
出版信息
Bull World Health Organ. 1971;45(4):423-9.
Abstract
Metrifonate, an organophosphorus compound, caused a decline in the number of microfilariae in domestic cats experimentally infected with Brugia pahangi. It was found that the drug was active against both microfilariae and macrofilariae, but probably its greatest effect was on the macrofilarial stages. It is suggested that the drug should be used in filarial infections of man on a trial basis.
摘要
敌百虫，一种有机磷化合物，使实验感染彭亨布鲁线虫的家猫体内微丝蚴数量减少。研究发现该药物对微丝蚴和成虫均有活性，但可能其最大作用是针对成虫阶段。建议该药物应在人体丝虫感染中进行试验性使用。
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