尼日利亚北部扎里亚的脑膜炎球菌感染疫情。2. 不断变化的临床模式。
An epidemic of meningococcal infection at Zaria, Northern Nigeria. 2. The changing clinical pattern.
作者信息
Greenwood B M, Cleland P G, Haggie M H, Lewis L S, Macfarlane J T, Taqi A, Whittle H C
出版信息
Trans R Soc Trop Med Hyg. 1979;73(5):563-6. doi: 10.1016/0035-9203(79)90053-1.
PMID:531910
Abstract
1,003 patients with meningococcal disease admitted to a single hospital during the course of a three-month epidemic were studied. A progressive decline in mortality, especially among patients with acute meningococcaemia, and a falling incidence of systemic and severe neurological complications among patients with meningitis were observed. It is suggested that the virulence of the causative group A meningococcus declined as the epidemic progressed.
摘要
在一场为期三个月的疫情期间，对一家医院收治的1003例脑膜炎球菌病患者进行了研究。观察到死亡率呈逐渐下降趋势，尤其是急性脑膜炎球菌血症患者，并且脑膜炎患者出现全身及严重神经并发症的发生率也在下降。有人认为，随着疫情的发展，致病性A群脑膜炎球菌的毒力有所下降。
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