Stenqvist O, Bagge U
Acta Otolaryngol. 1979;88(5-6):451-4. doi: 10.3109/00016487909137192.
A method is described for the intravital microscopic observations of rabbit tracheal mucosa microcirculation during compression with a thin, transparent high volume cuff. The cuff pressure (CP) required to cause complete ischemia in the mucosa over the cartilages was measured and a correlation was found to the mean arterial blood pressure (MAP). Ischemia was not observed below CP-MAP ratios of 0.40 for untreated animals or below 0.44 for animals where the MAP had been elevated by adrenalin. However, marked reduction of the microvascular blood flow was present at lower CP-MAP ratios, 0.2-0.3, which at a MAP of 75 mmHg corresponds to cuff pressures of 15-20 mmHg. It is therefore advocated that endotracheal cuff pressures are kept below these values to avoid ischemic tissue injury.
本文描述了一种在使用薄的、透明的大容量袖带进行压迫时对兔气管黏膜微循环进行活体显微镜观察的方法。测量了导致软骨上方黏膜完全缺血所需的袖带压力（CP），并发现其与平均动脉血压（MAP）存在相关性。对于未治疗的动物，当CP-MAP比值低于0.40时未观察到缺血；对于通过肾上腺素使MAP升高的动物，当CP-MAP比值低于0.44时未观察到缺血。然而，在较低的CP-MAP比值（0.2-0.3）时，微血管血流明显减少，在MAP为75 mmHg时，这对应于袖带压力为15-20 mmHg。因此，提倡将气管内袖带压力保持在这些值以下，以避免缺血性组织损伤。
