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脂肪组织细胞构成——代谢方面。1974 - 1975年哥德堡女性人群研究。

Adipose tissue cellularity--metabolic aspects. The population study of women in Göteborg 1974-1975.

作者信息

Noppa H, Bengtsson C, Isaksson B, Smith U

出版信息

Acta Med Scand. 1979;206(6):501-6.

PMID:532712
Abstract

A representative population sample of middle-aged women was studied in 1974-75. In a subsample, body composition and adipose tissue cellularity variables were determined and individuals with a particular clinical disorder were compared with the total subsample. Women with diabetes mellitus had more body fat and higher fat cell weights and larger fat cell members, whereas these variables did not differ in women with IHD or hypertension compared with the total subsample. Total body fat correlated with arterial BPs, fasting blood glucose, serum lipids and serum uric acid. The correlations were stronger than those reported previously by us between weight index and these variables. In univariate analyses, fat cell weight correlated with systolic BP, serum triglycerides and serum uric acid, and fat cell number with diastolic BP, fasting blood glucose and serum uric acid. In multivariate analyses, when due allowance was made for total body fat, the correlations between these variables and fat cell weight or fat cell number did not reach statistical significance.

摘要

1974 - 1975年对具有代表性的中年女性人群样本进行了研究。在一个子样本中,测定了身体成分和脂肪组织细胞变量,并将患有特定临床疾病的个体与整个子样本进行比较。糖尿病女性的体脂更多、脂肪细胞重量更高且脂肪细胞数量更多,而与整个子样本相比,患有缺血性心脏病(IHD)或高血压的女性在这些变量上并无差异。全身脂肪与动脉血压、空腹血糖、血脂和血清尿酸相关。这些相关性比我们之前报道的体重指数与这些变量之间的相关性更强。在单变量分析中,脂肪细胞重量与收缩压、血清甘油三酯和血清尿酸相关,脂肪细胞数量与舒张压、空腹血糖和血清尿酸相关。在多变量分析中,当对全身脂肪进行适当考虑时,这些变量与脂肪细胞重量或脂肪细胞数量之间的相关性未达到统计学显著性。

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