控制大肠杆菌对莽草酸摄取的基因。
Gene controlling the uptake of shikimic acid by Escherichia coli.
作者信息
Pittard J, Wallace B J
出版信息
J Bacteriol. 1966 Oct;92(4):1070-5. doi: 10.1128/jb.92.4.1070-1075.1966.
Abstract
Pittard, James (University of Melbourne, Melbourne, Australia), and B. J. Wallace. Gene controlling the uptake of shikimic acid by Escherichia coli. J. Bacteriol. 92:1070-1075. 1966.-Mutants possessing an impaired ability to take up exogenously supplied shikimic acid were isolated. Mutants showing either a complete or partial loss of this activity were found. The mutations have been mapped on the Escherichia coli chromosome and occur in a single gene, situated near to the cluster of genes concerned with histidine biosynthesis. The uptake of dehydroshikimic acid was also affected by these mutations, suggesting a common mechanism for the uptake of these two related intermediates of aromatic biosynthesis.
摘要
皮塔德，詹姆斯（澳大利亚墨尔本大学，墨尔本），以及B. J. 华莱士。控制大肠杆菌摄取莽草酸的基因。《细菌学杂志》92:1070 - 1075。1966年。——分离出了摄取外源供应莽草酸能力受损的突变体。发现了完全或部分丧失这种活性的突变体。这些突变已定位在大肠杆菌染色体上，且发生在一个单一基因中，该基因位于与组氨酸生物合成相关的基因簇附近。脱氢莽草酸的摄取也受这些突变影响，这表明这两种相关的芳香族生物合成中间体的摄取存在共同机制。
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