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控制大肠杆菌对莽草酸摄取的基因。

Gene controlling the uptake of shikimic acid by Escherichia coli.

作者信息

Pittard J, Wallace B J

出版信息

J Bacteriol. 1966 Oct;92(4):1070-5. doi: 10.1128/jb.92.4.1070-1075.1966.

DOI:10.1128/jb.92.4.1070-1075.1966
PMID:5332864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC276380/
Abstract

Pittard, James (University of Melbourne, Melbourne, Australia), and B. J. Wallace. Gene controlling the uptake of shikimic acid by Escherichia coli. J. Bacteriol. 92:1070-1075. 1966.-Mutants possessing an impaired ability to take up exogenously supplied shikimic acid were isolated. Mutants showing either a complete or partial loss of this activity were found. The mutations have been mapped on the Escherichia coli chromosome and occur in a single gene, situated near to the cluster of genes concerned with histidine biosynthesis. The uptake of dehydroshikimic acid was also affected by these mutations, suggesting a common mechanism for the uptake of these two related intermediates of aromatic biosynthesis.

摘要

皮塔德,詹姆斯(澳大利亚墨尔本大学,墨尔本),以及B. J. 华莱士。控制大肠杆菌摄取莽草酸的基因。《细菌学杂志》92:1070 - 1075。1966年。——分离出了摄取外源供应莽草酸能力受损的突变体。发现了完全或部分丧失这种活性的突变体。这些突变已定位在大肠杆菌染色体上,且发生在一个单一基因中,该基因位于与组氨酸生物合成相关的基因簇附近。脱氢莽草酸的摄取也受这些突变影响,这表明这两种相关的芳香族生物合成中间体的摄取存在共同机制。

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本文引用的文献

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[The biosynthesis of beta-galactosidase (lactase) in Escherichia coli; the specificity of induction].[大肠杆菌中β-半乳糖苷酶(乳糖酶)的生物合成;诱导的特异性]
Biochim Biophys Acta. 1951 Nov;7(4):585-99. doi: 10.1016/0006-3002(51)90072-8.
2
Genetic variation in the sex factor of Escherichia coli.大肠杆菌性别因子的遗传变异。
J Bacteriol. 1960 Mar;79(3):321-30. doi: 10.1128/jb.79.3.321-330.1960.
3
Distribution and function of genes concerned with aromatic biosynthesis in Escherichia coli.大肠杆菌中与芳香族生物合成相关基因的分布与功能
J Bacteriol. 1966 Apr;91(4):1494-508. doi: 10.1128/jb.91.4.1494-1508.1966.