van Doorn A W
Artif Organs. 1979 May;3(2):190-2. doi: 10.1111/j.1525-1594.1979.tb01038.x.
Large amounts (250 liters) of dialysate fluid are needed for dialysis of patients with chronic kidney diseases. A reduction of these amounts is obtainable by regeneration. With the Redy system, in which urea is decomposed by the enzyme urease, only 5.5 liters of dialysate is used. Other systems depending solely on sorption of urea still need excessive amounts of sorbents and no alternative, in the form of stable chemical binding, is available. If, therefore, further reduction of dialysate volume is desired, the problem of urea removal must be solved.
慢性肾病患者进行透析需要大量(250升)透析液。通过再生可减少这些用量。在Redy系统中,尿素由脲酶分解,仅需使用5.5升透析液。其他仅依靠尿素吸附的系统仍需要大量吸附剂,并且不存在以稳定化学结合形式的替代方法。因此,如果希望进一步减少透析液体积,就必须解决尿素清除问题。