Trafford A, Ireland R, Evans R
Artif Organs. 1979 Aug;3(3):249-52. doi: 10.1111/j.1525-1594.1979.tb01058.x.
Studies are reported on the use of short dialysis, sequential ultrafiltration/short dialysis and hemoperfusion in chronic renal failure. Short dialysis (less than 12 hours/week) is a satisfactory regime with good patient acceptance, adequate small and middle molecule clearance and control of fluid and blood pressure. Sequential ultrafiltration in the first hour improves fluid removal and reduces the side effects of dialysis. The addition of hemoperfusion increases clearance of small and middle molecules and has little effect on the osmolality of the serum. Thus, it does not increase the side effects of dialysis. Preliminary results suggest that hemoperfusion may be useful in the treatment of chronic renal failure in combination with ultrafiltration and dialysis.
报告了关于在慢性肾衰竭中使用短程透析、序贯超滤/短程透析和血液灌流的研究。短程透析（每周少于12小时）是一种令人满意的方案，患者接受度良好，对小分子和中分子有足够的清除率，并能控制液体和血压。在第一小时进行序贯超滤可改善液体清除并减少透析的副作用。添加血液灌流可增加小分子和中分子的清除率，且对血清渗透压影响很小。因此，它不会增加透析的副作用。初步结果表明，血液灌流与超滤和透析联合应用可能对慢性肾衰竭的治疗有用。
