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不同透析策略下的血清色谱图

Serum chromatographic pattern in different dialysis strategies.

作者信息

Ringoir S, De Smet R

出版信息

Int J Artif Organs. 1978 Sep;1(5):218-23.

PMID:689764
Abstract

In different dialysis strategies (hemodialysis with Gambro 1.5 m2, RP6 1 m2, Vita 2 1.2 m2), sequential ultrafiltration with RP 6 (1 hour ultrafiltration followed by 3 hours of hemodialysis and hemoperfusion with Absorba 300 C) serum chromatographic pattern and medium size molecules were studied with Sephadex G 15 chromatography. The removal of the studied medium size molecules is not different from one dialyzer to another. Serum levels were generally halved by the dialysis. In the ultrafiltration fluid a considerable amount of medium size molecules was found. There is no difference between RP 6 in open or in closed system. The absorbing capacity of the Absorba 300 C was blocked after one hour for medium size molecules in the patient under study.

摘要

在不同的透析策略(使用金宝1.5平方米、RP6 1平方米、Vita 2 1.2平方米进行血液透析)中,采用RP 6进行序贯超滤(1小时超滤,随后3小时血液透析并使用Absorba 300 C进行血液灌流),通过葡聚糖凝胶G 15色谱法研究血清色谱图谱和中等大小分子。所研究的中等大小分子的清除率在不同透析器之间并无差异。透析后血清水平通常减半。在超滤液中发现了相当数量的中等大小分子。开放系统或封闭系统中的RP 6之间没有差异。在所研究的患者中,Absorba 300 C对中等大小分子的吸收能力在1小时后被阻断。

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