影响霍乱弧菌体外皮肤渗透因子产生的因素。
Factors influencing in vitro skin permeability factor production by Vibrio cholerae.
作者信息
Richardson S H
出版信息
J Bacteriol. 1969 Oct;100(1):27-34. doi: 10.1128/jb.100.1.27-34.1969.
Abstract
The development of a new semisynthetic medium which stimulates in vitro production of the skin permeability factor (PF) by Vibrio cholerae is described. The effects of pH, aeration, temperature, and length of incubation on PF formation or release in strain 569B and several other strains, or both, are compared. Data are presented which show that maximal PF accumulation occurs during a transitional period of growth joining the exponential and stationary phases of the growth cycle. PF elaboration is completed well ahead of any visible signs of lysis in the culture and the PF activity appears to be proportional to the length of the linear growth phase. Possible mechanisms of toxigenicity and the nature of PF are discussed.
摘要
本文描述了一种新型半合成培养基的研发，该培养基可刺激霍乱弧菌在体外产生皮肤渗透因子（PF）。比较了pH、通气、温度和培养时间对569B菌株及其他几种菌株中PF形成或释放的影响，或对两者的影响。所呈现的数据表明，PF的最大积累发生在生长周期中连接指数生长期和稳定期的过渡生长阶段。PF的合成在培养物出现任何可见裂解迹象之前就已完成，且PF活性似乎与线性生长阶段的长度成正比。文中还讨论了产毒的可能机制以及PF的性质。
相似文献
1
Factors influencing in vitro skin permeability factor production by Vibrio cholerae.影响霍乱弧菌体外皮肤渗透因子产生的因素。
J Bacteriol. 1969 Oct;100(1):27-34. doi: 10.1128/jb.100.1.27-34.1969.
2
In vitro production of choleragen and vascular permeability factor by Vibrio cholerae.霍乱弧菌体外产生霍乱毒素和血管通透性因子。
J Bacteriol. 1968 Jul;96(1):126-30. doi: 10.1128/jb.96.1.126-130.1968.
3
Fine structure of Vibrio cholerae during toxin production.霍乱弧菌产毒素过程中的精细结构
J Bacteriol. 1969 Dec;100(3):1393-401. doi: 10.1128/jb.100.3.1393-1401.1969.
4
Permeability and enterotoxic factors of nonagglutinable vibrios Vibrio alcaligenes and Vibrio parahaemolyticus.非凝集性弧菌（产碱弧菌和副溶血性弧菌）的通透性及肠毒素因子
Appl Microbiol. 1971 Dec;22(6):1159-61. doi: 10.1128/am.22.6.1159-1161.1971.
5
Biochemistry of vibrio cholerae virulence. II. Skin permeability factor-cholera enterotoxin production in a chemically defined medium.霍乱弧菌毒力的生物化学。II. 在化学成分确定的培养基中皮肤渗透因子-霍乱肠毒素的产生。
Infect Immun. 1971 Nov;4(5):611-8. doi: 10.1128/iai.4.5.611-618.1971.
6
Production of Biologically Active Substances by Two Strains of Vibrio cholerae.两株霍乱弧菌产生的生物活性物质。
Infect Immun. 1970 Jan;1(1):80-7. doi: 10.1128/iai.1.1.80-87.1970.
7
Production of cholera toxin-like toxin by Vibrio mimicus and non-O1 Vibrio cholerae: batch culture conditions for optimum yields and isolation of hypertoxigenic lincomycin-resistant mutants.拟态弧菌和非O1群霍乱弧菌产生霍乱毒素样毒素：最佳产量的分批培养条件及高产毒林可霉素抗性突变体的分离
Infect Immun. 1983 Nov;42(2):501-9. doi: 10.1128/iai.42.2.501-509.1983.
8
Preparation of the vascular permeability factor of Vibrio cholerae.霍乱弧菌血管通透性因子的制备
J Bacteriol. 1966 Sep;92(3):793-5. doi: 10.1128/jb.92.3.793-795.1966.
9
Vibrio cholerae: production of toxin by a nonpathogenic strain.霍乱弧菌：非致病菌株产生毒素。
J Infect Dis. 1970 Dec;122(6):540-3. doi: 10.1093/infdis/122.6.540.
10
Some differential growth characteristics of Vibrio cholerae and Vibrio metschnikovii in liquid medium.霍乱弧菌和梅契尼科夫弧菌在液体培养基中的一些生长差异特性。
J Hyg Epidemiol Microbiol Immunol. 1991;35(1):51-5.
引用本文的文献
1
Are obstructive sleep apnea and sleep improved in response to multidisciplinary weight loss interventions in youth with obesity? A systematic review and meta-analysis.肥胖青少年接受多学科减肥干预后，阻塞性睡眠呼吸暂停和睡眠情况是否得到改善？系统评价和荟萃分析。
Int J Obes (Lond). 2020 Apr;44(4):753-770. doi: 10.1038/s41366-019-0497-7. Epub 2020 Jan 7.
2
Seasonality and toxigenicity ofVibrio cholerae non-01 isolated from different components of pond ecosystems of Dhaka City, Bangladesh.孟加拉国达卡市池塘生态系统不同组成部分分离的非 01 霍乱弧菌的季节性和产毒特性。
World J Microbiol Biotechnol. 1992 Mar;8(2):160-3. doi: 10.1007/BF01195838.
3
Biochemistry of Vibrio cholerae Virulence I. Purification and Biochemical Properties of PF/Cholera Enterotoxin.霍乱弧菌毒力的生物化学 I. PF/霍乱肠毒素的纯化和生化特性。
Infect Immun. 1970 Jun;1(6):546-54. doi: 10.1128/iai.1.6.546-554.1970.
4
Virulence gene regulation inside and outside.毒力基因的内外调控
Philos Trans R Soc Lond B Biol Sci. 2000 May 29;355(1397):657-65. doi: 10.1098/rstb.2000.0606.
5
Vibrio parahaemolyticus has a homolog of the Vibrio cholerae toxRS operon that mediates environmentally induced regulation of the thermostable direct hemolysin gene.副溶血性弧菌有一个与霍乱弧菌toxRS操纵子同源的基因，该操纵子介导环境诱导的耐热直接溶血素基因调控。
J Bacteriol. 1993 Jun;175(12):3844-55. doi: 10.1128/jb.175.12.3844-3855.1993.
6
Vibrio cholerae hlyB is a member of the chemotaxis receptor gene family.霍乱弧菌hlyB是趋化受体基因家族的成员。
Protein Sci. 1993 Sep;2(9):1532-5. doi: 10.1002/pro.5560020918.
7
Cholera.霍乱
Clin Microbiol Rev. 1995 Jan;8(1):48-86. doi: 10.1128/CMR.8.1.48.
8
Lincomycin increases synthetic rate and periplasmic pool size for cholera toxin.林可霉素可提高霍乱毒素的合成速率和周质池大小。
J Bacteriol. 1980 Jul;143(1):441-7. doi: 10.1128/jb.143.1.441-447.1980.
9
Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli.在携带编码大肠杆菌不耐热肠毒素的质粒的霍乱弧菌菌株中研究霍乱弧菌毒素分泌机制。
Proc Natl Acad Sci U S A. 1984 Dec;81(24):7752-6. doi: 10.1073/pnas.81.24.7752.
10
Fine structure of Vibrio cholerae during toxin production.霍乱弧菌产毒素过程中的精细结构
J Bacteriol. 1969 Dec;100(3):1393-401. doi: 10.1128/jb.100.3.1393-1401.1969.
本文引用的文献
1
PATHOGENESIS EXPERIMENTAL CHOLERA IN INFANT RABBITS. I. OBSERVATIONS ON THE INTRAINTESTINAL INFECTION AND EXPERIMENTAL CHOLERA PRODUCED WITH CELL-FREE PRODUCTS.幼兔实验性霍乱的发病机制。I. 关于无细胞产物引起的肠道内感染及实验性霍乱的观察
J Infect Dis. 1964 Jun;114:203-16. doi: 10.1093/infdis/114.3.203.
2
[STUDY OF VIBRIO CHOLERAE USING THE ELECTRON MICROSCOPE AND THE RELATION BETWEEN THE MORPHOLOGICAL ASPECT AND O AGGLUTINATION].[利用电子显微镜对霍乱弧菌及形态学特征与O凝集反应之间关系的研究]
Bull World Health Organ. 1963;29(6):767-71.
3
Further observations on cholera enterotoxin.关于霍乱肠毒素的进一步观察
Trans R Soc Trop Med Hyg. 1962 May;56:241-5. doi: 10.1016/0035-9203(62)90161-x.
4
Pathogenesis of experimental cholera. Effect of choleragen on vascular permeability.实验性霍乱的发病机制。霍乱毒素对血管通透性的影响。
Lab Invest. 1966 Oct;15(10):1601-9.
5
The titration of cholera toxin and antitoxin in the rabbit ileal loop.兔肠袢中霍乱毒素与抗毒素的滴定
J Infect Dis. 1966 Dec;116(5):606-14. doi: 10.1093/infdis/116.5.606.
6
Preparation of the vascular permeability factor of Vibrio cholerae.霍乱弧菌血管通透性因子的制备
J Bacteriol. 1966 Sep;92(3):793-5. doi: 10.1128/jb.92.3.793-795.1966.
7
Experimental cholera in humans.人类实验性霍乱
Br Med J. 1966 Jan 15;1(5480):140-2. doi: 10.1136/bmj.1.5480.140.
8
A permeability factor (toxin) found in cholera stools and culture filtrates and its neutralization by convalescent cholera sera.在霍乱粪便和培养滤液中发现的一种通透因子（毒素）及其被霍乱恢复期血清中和的情况。
Nature. 1965 Aug 7;207(997):614-6. doi: 10.1038/207614a0.
9
Experimental cholera in the rabbit ligated intestine: ion and water accumulation in the duodenum, ileum and colon.兔结扎肠段的实验性霍乱：十二指肠、回肠和结肠中的离子与水分蓄积
J Infect Dis. 1968 Oct;118(4):349-59. doi: 10.1093/infdis/118.4.349.
10
Isolation of cholera toxins by dextran sulfate precipitation.通过硫酸葡聚糖沉淀法分离霍乱毒素。
J Bacteriol. 1968 Oct;96(4):1443-5. doi: 10.1128/jb.96.4.1443-1445.1968.
Zotero 插件