人血浆中激肽形成因子的分离。
Separation of kinin-forming factors in human plasma.
作者信息
Eisen V, Glanville K L
出版信息
Br J Exp Pathol. 1969 Oct;50(5):427-37.
Abstract
The kinin-forming proteases in human serum were studied. Two serum kallikreins, enzymes acting directly and specifically on kinin-yielding globulin (kininogen), were separated by ion-exchange chromatography. They were differentiated from plasmin by their high ratio kinin-forming/esterolytic activity, by the absence of fibrinolytic activity, and by a lower Michaelis-Menten constant for the hydrolysis of an arginine ester. Their relationship to enzymes which induce kinin formation mainly by activating serum prekallikreins, was studied.
摘要
对人血清中形成激肽的蛋白酶进行了研究。通过离子交换色谱法分离出了两种血清激肽释放酶，这两种酶直接且特异性地作用于产生激肽的球蛋白（激肽原）。它们与纤溶酶的区别在于，其形成激肽/酯水解活性的比例较高，缺乏纤溶活性，并且水解精氨酸酯的米氏常数较低。研究了它们与主要通过激活血清前激肽释放酶来诱导激肽形成的酶之间的关系。
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J Physiol. 1963 May;166(3):496-513. doi: 10.1113/jphysiol.1963.sp007119.
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Studies on plant amylases: The effect of starch concentration upon the velocity of hydrolysis by the amylase of germinated barley.植物淀粉酶的研究：淀粉浓度对发芽大麦淀粉酶水解速度的影响。
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