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Separation of kinin-forming factors in human plasma.

作者信息

Eisen V, Glanville K L

出版信息

Br J Exp Pathol. 1969 Oct;50(5):427-37.

Abstract

The kinin-forming proteases in human serum were studied. Two serum kallikreins, enzymes acting directly and specifically on kinin-yielding globulin (kininogen), were separated by ion-exchange chromatography. They were differentiated from plasmin by their high ratio kinin-forming/esterolytic activity, by the absence of fibrinolytic activity, and by a lower Michaelis-Menten constant for the hydrolysis of an arginine ester. Their relationship to enzymes which induce kinin formation mainly by activating serum prekallikreins, was studied.

摘要

引用本文的文献

1
On the endogenous mechanism of kinin release. I. Attempts at discriminating kallikreins.
Naunyn Schmiedebergs Arch Pharmakol. 1971;269(1):85-100. doi: 10.1007/BF01422018.
2
Inhibitors of kallikrein in human plasma.
J Clin Invest. 1972 Jul;51(7):1611-23. doi: 10.1172/jci106962.

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