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Avoidance learning: long-lasting deficits after temporal lobe seizure.

作者信息

Belluzzi J D, Grossman S P

出版信息

Science. 1969 Dec 12;166(3911):1435-7. doi: 10.1126/science.166.3911.1435.

DOI:10.1126/science.166.3911.1435
PMID:5350349
Abstract

Microinjections of carbachol (carbamylcholine chloride) into the amygdaloid complex of rats produced behavioral and electrophysiological seizures which subsided within 24 hours. A persisting functional change caused a deficit in avoidance learning 1 to 3 weeks after the seizure. A cholinergic system is implicated by the fact that cholinergic blockade (scopolamine) of the amygdala during training reversed the effects of the seizures induced by carbachol.

摘要

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