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用色甘酸钠治疗的慢性哮喘患者的血气张力和功能残气量的变化。

Changes in blood gas tensions and functional residual capacity chronic asthmatics treated with disodium cromoglycate.

作者信息

Lane D J

出版信息

Br Med J. 1969 Dec 20;4(5685):710-2. doi: 10.1136/bmj.4.5685.710.

Abstract

Twenty chronic asthmatic subjects were treated with disodium cromoglycate in open trial. Although in the group as a whole spirometric findings improved, some patients showed a significant increase in arterial oxygen tension or a significant fall in functional residual capacity without any appreciable changes in spirometry. These changes may partly explain the clinical efficacy of this drug.

摘要

20名慢性哮喘患者接受了色甘酸钠的开放试验治疗。尽管总体而言,该组患者的肺功能检查结果有所改善,但部分患者动脉血氧分压显著升高或功能残气量显著下降,而肺功能检查却无明显变化。这些变化可能部分解释了该药的临床疗效。

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本文引用的文献

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VARIATION OF DRUG ACTION ON AIRWAY OBSTRUCTION IN MAN.
Thorax. 1964 Sep;19(5):406-15. doi: 10.1136/thx.19.5.406.
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Lung volumes in exacerbations of asthma.哮喘加重期的肺容积
Am J Med. 1966 Aug;41(2):259-73. doi: 10.1016/0002-9343(66)90021-0.
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Trial of disodium cromoglycate in bronchial asthma.色甘酸钠治疗支气管哮喘的试验。
Br Med J. 1969 Mar 1;1(5643):552-4. doi: 10.1136/bmj.1.5643.552.

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