Lane D J
Br Med J. 1969 Dec 20;4(5685):710-2. doi: 10.1136/bmj.4.5685.710.
Twenty chronic asthmatic subjects were treated with disodium cromoglycate in open trial. Although in the group as a whole spirometric findings improved, some patients showed a significant increase in arterial oxygen tension or a significant fall in functional residual capacity without any appreciable changes in spirometry. These changes may partly explain the clinical efficacy of this drug.
20名慢性哮喘患者接受了色甘酸钠的开放试验治疗。尽管总体而言,该组患者的肺功能检查结果有所改善,但部分患者动脉血氧分压显著升高或功能残气量显著下降,而肺功能检查却无明显变化。这些变化可能部分解释了该药的临床疗效。