Exercise asthma and disodium cromoglycate.
作者信息
Poppius H, Muittari A, Kreus K E, Korhonen O, Viljanen A
出版信息
Br Med J. 1970 Nov 7;4(5731):337-9. doi: 10.1136/bmj.4.5731.337.
Abstract
Exercise-induced asthma (defined as a fall in PEF of at least 25% of the pre-exercise value) was studied in adult patients with uncomplicated asthma. This was found to occur in 22 out of 52 patients. Pre-exercise inhalation of disodium cromoglycate reduced the mean fall in PEF after maximal exercise from 50% of the pre-exercise value to 23% (open assessment in 11 cases). After submaximal exercise for eight minutes the reduction was from 18% to 10% (double-blind crossover study in 28 cases). It is concluded that disodium cromoglycate partly inhibits the increase of airways resistance after exercise in asthmatic patients.
摘要
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