Wagner J A, Miles D S, Horvath S M, Reyburn J A
J Appl Physiol Respir Environ Exerc Physiol. 1979 Dec;47(6):1223-7. doi: 10.1152/jappl.1979.47.6.1223.
Six healthy women (22--34 yr of age) performed maximal bicycle work in a hypobaric chamber at sea level and at simulated altitudes of 2,130 and 3,050 m (barometric pressures, 758, 586, and 523 Torr). Maximal oxygen uptake (VO2max) decreased 10 and 15% from sea-level values at 2,130 and 3,050 m, respectively. At these altitudes minute ventilation (VEBTPS) increased 17 and 22% respectively, a consequence of increased respiratory rate (fR). Respiratory exchange ratios increased 10 and 14%, and oxygen pulse decreased 9 and 12%, respectively, at 2,130 and 3,050 m. Maximal blood lactates, heart rates, cardiac outputs, and plasma volume shifts were unaffected by these altitudes. Although during maximal work the percentage increases in VEBTPS, fR, and R that resulted from altitude exposure were greater in women than those previously reported for men, the decrements in VO2max were comparable to those in men. The results show that relative to their performance at sea level, men and women have equal ability to perform maximal work at altitudes up to 3,050 m.
六名健康女性（年龄在22 - 34岁之间）在海平面以及模拟海拔2130米和3050米（气压分别为758、586和523托）的低压舱中进行了最大强度的自行车运动。最大摄氧量（VO2max）在海拔2130米和3050米时分别比海平面值降低了10%和15%。在这些海拔高度，每分通气量（VEBTPS）分别增加了17%和22%，这是呼吸频率（fR）增加的结果。在海拔2130米和3050米时，呼吸交换率分别增加了10%和14%，氧脉搏分别降低了9%和12%。最大血乳酸、心率、心输出量和血浆量变化不受这些海拔高度的影响。尽管在最大强度运动期间，女性因海拔暴露导致的VEBTPS、fR和R的百分比增加幅度大于先前报道的男性，但VO2max的下降幅度与男性相当。结果表明，相对于她们在海平面的表现，男性和女性在高达3050米的海拔高度进行最大强度运动的能力相当。
