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用于淋巴闪烁造影的两种锝-99m标记放射性药物的比较:简要通信

A comparison of two technetium-99m-labeled radiopharmaceuticals for lymphoscintigraphy: concise communication.

作者信息

Kaplan W D, Davis M A, Rose C M

出版信息

J Nucl Med. 1979 Sep;20(9):933-7.

PMID:536838
Abstract

A comparison of stannous phytate and antimony sulfide colloid, both labeled with Tc-99m, was conducted during the performance of internal mammary lymphoscintigraphy in 46 patients. Thirteen of these patients were randomized to receive both radiotracers in two consecutive studies. The results indicated a statistical difference between agents; Tc-99m antimony sulfide allowed visualization of a greater number of more intense nodes, better delineation of the total length of the internal mammary lymph-node chain, and a more consistent visualization of supraclavicular nodes. Although previously published animal data suggest utility of Tc-99m stannous phytate for lymph-node imaging, Tc-99m antimony sulfide was shown in this clinical comparison to provide a more reliable representation of lymph-node anatomy.

摘要

在46例患者进行内乳淋巴闪烁显像期间,对均用Tc-99m标记的植酸亚锡和硫化锑胶体进行了比较。其中13例患者在两项连续研究中随机接受了两种放射性示踪剂。结果表明两种制剂之间存在统计学差异;Tc-99m硫化锑能使更多数量、更强的淋巴结显影,能更好地勾勒出内乳淋巴结链的全长,锁骨上淋巴结的显影也更一致。尽管先前发表的动物数据表明Tc-99m植酸亚锡可用于淋巴结成像,但在本次临床比较中,Tc-99m硫化锑能更可靠地显示淋巴结解剖结构。

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A comparison of two technetium-99m-labeled radiopharmaceuticals for lymphoscintigraphy: concise communication.用于淋巴闪烁造影的两种锝-99m标记放射性药物的比较:简要通信
J Nucl Med. 1979 Sep;20(9):933-7.
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Effect of increased (99m)Tc/(99)Tc ratios on count rates in sentinel node procedures: a randomised study.
增加的(99m)锝/(99)锝比率对前哨淋巴结手术中计数率的影响:一项随机研究。
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Evaluation of 99mTc-dextran as a lymphoscintigraphic agent in rabbits.
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Two lymphoscintigraphic agents compared in vitro and in vivo in rabbit knees.两种淋巴闪烁造影剂在兔膝关节的体外和体内比较。
Eur J Nucl Med. 1990;16(8-10):639-41. doi: 10.1007/BF00998162.