Nyman D, da Silva M A, Widmer L K, Duckert F
Thromb Diath Haemorrh. 1975 Nov 15;34(2):498-503.
Brinase was administered intra-arterially in 16 patients with thrombotic or embolic arterial occlusions. Angiography could be performed before and after treatment in 13 patients. Thrombolysis was obtained in 3 of 9 patients with thrombotic and in 3 of 4 patients with embolic occlusions. In 3 patients severe local side effects occurred.
对16例血栓形成或栓塞性动脉闭塞患者进行动脉内注射链激酶。13例患者在治疗前后进行了血管造影。9例血栓形成患者中有3例、4例栓塞性闭塞患者中有3例实现了溶栓。3例患者出现严重局部副作用。