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缝合材料对感染伤口细菌存活的影响。一项实验研究。

Effect of suture materials on bacterial survival in infected wounds. An experimental study.

作者信息

Osterberg B, Blomstedt B

出版信息

Acta Chir Scand. 1979;145(7):431-4.

PMID:539325
Abstract

A non-capilllary and a capillary suture material were compared as regards the course of Staphylococcus areus infection at the site of implantation. The materials were implanted in the muscle of the rat, and bacterial counts were made at intervals over 41 days. The number of bacteria recovered at the implantation site during the test period decreased steadily and was significantly lower for the non-capillary than for the capillary materials. In the latter case the bacterial counts did not fall far below the initial value at inoculation. The number of bacteria isolated from the suture thread in relation to the total number from the thread and the surrounding muscle was significantly greater for the capillary material. The difference in the results for the two types of suture materials might be ascribed to differences in the extent to which the bacteria are exposed to the body's defence mechanism; in the case of the capillary suture material the bacteria would tend to be protected through their enclosure in the interstices of the material.

摘要

对一种非毛细血管缝合材料和一种毛细血管缝合材料在植入部位金黄色葡萄球菌感染过程方面进行了比较。将这些材料植入大鼠肌肉中,并在41天内定期进行细菌计数。在测试期间,植入部位回收的细菌数量稳步下降,非毛细血管材料的细菌数量明显低于毛细血管材料。在后一种情况下,细菌计数并未远低于接种时的初始值。从缝合线分离出的细菌数量与从缝合线和周围肌肉分离出的细菌总数相比,毛细血管材料的这一数量明显更多。两种缝合材料结果的差异可能归因于细菌暴露于机体防御机制的程度不同;对于毛细血管缝合材料,细菌往往通过被包裹在材料的间隙中而得到保护。

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