Bresson J L, Prévot C, Rappaport R, Czernichow P, Schmitz J, Rey J
Arch Fr Pediatr. 1979 Nov;36(9 Suppl):XIII-XVIII.
Sixteen children, aged 5-19 years with late diagnosed coeliac disease who presented with significant growth delay were studied. Plasma somatomedin was decreased in all patients (mean 0.28 +/- 0.1) but the circulating growth hormone levels were normal in 12 patients. No inhibitory activity could be detected. Somatomedin activity was partially corrected in six patients who were re-examined after 3 months on a gluten free diet. This suggests that low somatomedin levels may be the result of the nutritional abnormalities during the active phase of the disease.
对16名年龄在5至19岁之间、患有晚期诊断乳糜泻且伴有明显生长发育迟缓的儿童进行了研究。所有患者的血浆生长调节素均降低（平均0.28 +/- 0.1），但12名患者的循环生长激素水平正常。未检测到抑制活性。6名患者在无麸质饮食3个月后重新检查，其生长调节素活性得到部分纠正。这表明生长调节素水平低可能是疾病活动期营养异常的结果。
