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无麸质饮食对5岁后确诊的患有生长发育迟缓的腹腔疾病儿童追赶生长及身高预后的影响。

Effects of a gluten-free diet on catch-up growth and height prognosis in coeliac children with growth retardation recognized after the age of 5 years.

作者信息

De Luca F, Astori M, Pandullo E, Sferlazzas C, Arrigo T, Sindoni A, Magazzù G

机构信息

Istituto di Clinica Pediatrica, Policlinico Universitario, Messina, Italy.

出版信息

Eur J Pediatr. 1988 Feb;147(2):188-91. doi: 10.1007/BF00442220.

DOI:10.1007/BF00442220
PMID:3366137
Abstract

The effects of a gluten-free diet on catch-up growth and predicted height were evaluated in 12 children with coeliac disease diagnosed after the age of 5 years and followed for 2-5.5 years. In the majority of the patients, height and bone age were retarded at the time of diagnosis. Under a gluten-free diet growth velocity, age-related height, predicted height and relative bone age increased, height for bone age slightly decreased. In four patients the predicted height remained below the target height, indicating incomplete catch-up growth.

摘要

对12名5岁后确诊的乳糜泻患儿进行了无麸质饮食对追赶生长和预测身高影响的评估,随访时间为2至5.5年。大多数患者在诊断时身高和骨龄落后。在无麸质饮食条件下,生长速度、年龄相关身高、预测身高和相对骨龄增加,骨龄对应的身高略有下降。4名患者的预测身高仍低于目标身高,表明追赶生长不完全。

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本文引用的文献

1
[Growth retardation in celiac disease. Report of 2 cases of dwarfism in siblings].[乳糜泻中的生长发育迟缓。一对患侏儒症的同胞兄妹病例报告]
Minerva Pediatr. 1980 Jul 31;32(14):857-62.
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[Coeliac dwarfism. Hormonal and growth studies in late diagnosed gluten intolerance (author's transl)].[乳糜泻侏儒症。晚期诊断出的麸质不耐受的激素及生长研究(作者译)]
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营养干预防治发育迟缓的关键窗口期。
Am J Clin Nutr. 2013 May;97(5):911-8. doi: 10.3945/ajcn.112.052332. Epub 2013 Apr 3.
4
Growth hormone impaired secretion and antipituitary antibodies in patients with coeliac disease and poor catch-up growth after a long gluten-free diet period: a causal association?乳糜泻患者在长期无麸质饮食后生长激素分泌受损及抗垂体抗体与生长追赶不良:存在因果关联吗?
Eur J Pediatr. 2006 Dec;165(12):897-903. doi: 10.1007/s00431-006-0182-4. Epub 2006 Aug 3.
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Linear catch-up growth.线性追赶生长
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What will be the adult height of coeliac patients?乳糜泻患者的成人身高会是多少?
Eur J Pediatr. 1991 Apr;150(6):407-9. doi: 10.1007/BF02093719.
儿童晚期乳糜泻的检测。关于临床表现和诊断标准的讨论。(初步结果)(作者译)
Pediatr Med Chir. 1981 Mar-Jun;3(2-3):189-92.
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Short stature and celiac disease: a relationship to consider even in patients with no gastrointestinal tract symptoms.
J Pediatr. 1983 Nov;103(5):708-11. doi: 10.1016/s0022-3476(83)80462-4.
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[Celiac disease and short stature].[乳糜泻与身材矮小]
Pediatr Med Chir. 1984 Jan-Feb;6(1):115-9.
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Short stature as the primary manifestation of coeliac disease.身材矮小作为乳糜泻的主要表现
Lancet. 1980 Nov 22;2(8204):1097-9. doi: 10.1016/s0140-6736(80)92538-6.
7
Standards for children's height at ages 2-9 years allowing for heights of parents.2至9岁儿童身高标准,考虑到父母的身高因素。
Arch Dis Child. 1970 Dec;45(244):755-62. doi: 10.1136/adc.45.244.755.
8
Coeliac disease in children of short stature without gastrointestinal symptoms.
Eur J Pediatr. 1986 Aug;145(3):185-6. doi: 10.1007/BF00446061.
9
Low serum somatomedin activity in celiac disease. A misleading aspect in growth failure from asymptomatic celiac disease.乳糜泻患者血清生长调节素活性降低。无症状乳糜泻导致生长发育迟缓的一个误导性方面。
Helv Paediatr Acta. 1978 Dec;33(6):509-16.
10
[Circulating somatomedin activity and growth hormone secretion. Changes during late diagnosed celiac disease and effects of treatment].[循环生长介素活性与生长激素分泌。晚发性乳糜泻期间的变化及治疗效果]
Arch Fr Pediatr. 1979 Nov;36(9 Suppl):XIII-XVIII.