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[离体存活大鼠肝脏中脂质过氧化的动力学]

[Kinetics of lipid peroxidation in isolated surviving rat livers].

作者信息

Dzhafarov A I

出版信息

Biull Eksp Biol Med. 1979 Nov;88(11):548-51.

PMID:540140
Abstract

The kinetics of accumulation of lipid peroxidation products (hydroperoxides as primary products and malonic dialdehyde and "fluorescent pigments" as secondary ones) was investigated in an isolated non-perfused and preliminarily perfused liver during aerobic incubation. In the course of surviving there takes place an intensive accumulation of primary, secondary and final products of lipid peroxidation whose kinetics is of an extreme character. The rate of this process in a non-perfused liver is considerably higher than in a preliminarily perfused liver.

摘要

在需氧孵育过程中,研究了分离的非灌注肝脏和预先灌注肝脏中脂质过氧化产物(作为初级产物的氢过氧化物以及作为次级产物的丙二醛和“荧光色素”)的积累动力学。在存活过程中,脂质过氧化的初级、次级和最终产物会大量积累,其动力学具有极端特征。该过程在非灌注肝脏中的速率明显高于预先灌注的肝脏。

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