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美托洛尔对动态血压的影响。

The effects of metoprolol on ambulatory blood pressure.

作者信息

Mann S, Craig M W, Altman D G, Melville D I, Raftery E B

出版信息

Clin Sci (Lond). 1979 Dec;57 Suppl 5:375s-377s. doi: 10.1042/cs057375s.

Abstract
  1. Continuous monitoring of arterial pressure was performed via an indwelling cannula over 24 h in 12 hypertensive patients before treatment and again 2-4 months after starting metoprolol (100 mg twice daily). 2. During treatment, heart rate and systolic and diastolic pressures were significantly reduced. 3. The circadian patterns of heart rate and blood pressure changes were similar before and during therapy.
摘要
  1. 在12例高血压患者治疗前,通过留置套管连续监测动脉压24小时,开始服用美托洛尔(每日两次,每次100毫克)2至4个月后再次进行监测。2. 治疗期间,心率以及收缩压和舒张压均显著降低。3. 治疗前后心率和血压变化的昼夜模式相似。

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