聚肌苷酸-聚胞苷酸抑制化学诱导的小鼠皮肤肿瘤发生。
Polyinosinic-polycytidylic acid inhibits chemically induced tumorigenesis in mouse skin.
作者信息
Gelboin H V, Levy H B
出版信息
Science. 1970 Jan 9;167(3915):205-7. doi: 10.1126/science.167.3915.205.
PMID:5409649
Abstract
Polyinosinic-polycytidylic acid administered intraperitoneally inhibits (i) the formation of skin tumors induced by a single topical application of 9,10-dimethylbenzanthracene followed by weekly applications of croton oil and (ii) the formation of skin tumors induced by a single large application of 9,10-dimethylbenzanthracene.
摘要
腹腔注射多聚肌苷酸-聚胞苷酸可抑制：（i）单次局部涂抹9,10-二甲基苯并蒽，随后每周涂抹巴豆油所诱发的皮肤肿瘤的形成；以及（ii）单次大量涂抹9,10-二甲基苯并蒽所诱发的皮肤肿瘤的形成。
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