通过诱导部分耐受性抑制迟发型超敏反应的体外研究。
In vitro studies of the suppression of delayed hypersensitivity by the induction of partial tolerance.
作者信息
Borel Y, David J R
出版信息
J Exp Med. 1970 Mar 1;131(3):603-10. doi: 10.1084/jem.131.3.603.
Abstract
Suppression of delayed hypersensitivity in vivo is correlated in vitro with the absence of macrophage migration inhibition in the presence of the antigen used to induce partial tolerance. The suppression of delayed hypersensitivity is antigen-specific in vivo as well as in vitro. The lymphocytes, and not the macrophages, are the cells involved in the induction of tolerance in terms of delayed hypersensitivity which is characterized by an absence of migratory factor activity.
摘要
体内迟发型超敏反应的抑制在体外与在用于诱导部分耐受性的抗原存在下巨噬细胞迁移抑制的缺失相关。迟发型超敏反应的抑制在体内和体外都是抗原特异性的。就以迁移因子活性缺失为特征的迟发型超敏反应而言，淋巴细胞而非巨噬细胞是参与耐受性诱导的细胞。
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Immunochemical studies on the specificity of cellular hypersensitivity. The in vitro inhibition of peritoneal exudate cell migration by cehmically defined antigens.细胞超敏反应特异性的免疫化学研究。化学确定的抗原对腹腔渗出细胞迁移的体外抑制作用。
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