Leibfried L, First N L
J Exp Zool. 1979 Dec;210(3):575-80. doi: 10.1002/jez.1402100322.
Lowering the external concentrations of both Mg+2 and Ca+2 caused failure of meiotic resumption in vitro of bovine, oocyte-cumulus complexes. Lowering of external Ca+2 levels singly had no effect on either meiotic resumption or completion of the first meiotic division. Lowering of external Mg+2 concentrations alone, although having no effect on meiotic resumption in vitro when Ca+2 was present, did interfere with the completion of the first meiotic division. The result was arrest of oocyte maturation between germinal vesicle breakdown and formation of the first metaphase plate.
降低Mg+2和Ca+2的细胞外浓度会导致牛卵母细胞-卵丘复合体在体外减数分裂恢复失败。单独降低细胞外Ca+2水平对减数分裂恢复或第一次减数分裂的完成均无影响。单独降低细胞外Mg+2浓度，虽然在存在Ca+2时对体外减数分裂恢复没有影响，但确实会干扰第一次减数分裂的完成。结果是卵母细胞成熟在生发泡破裂和第一个中期板形成之间停滞。
