Role of divalent cations in the resumption of meiosis of rat oocytes.
作者信息
Tsafriri A, Bar-Ami S
出版信息
J Exp Zool. 1978 Aug;205(2):293-300. doi: 10.1002/jez.1402050213.
PMID:355599
Abstract
Resumption of meiotic maturation was induced in follicle-enclosed rat-oocytes by treatment with the divalent cationophore A23187 (10(-5)M). However, the same effect was attained by incubation in Ca++-deficient medium, even in the presence of EDTA or EGTA (1mM). The stability of the first polar body was increased under Ca++-deficient conditions. Neither the ionophore nor Ca++-deficient medium interfered with the spontaneous maturation of isolated oocytes of the rat. The experiments with cultured follicles suggest that redistribution of divalent cations may participate in the physiological control of meiosis in mammalian oocytes.
摘要
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