Wolff I, Wick G, Furthmayr H, Timpl R, Steffen C
Immunology. 1970 Jun;18(6):843-7.
In rabbit antisera to acid-soluble carp collagen two antibody fractions differing in specificity were demonstrated by passive haemagglutination. The antibody fractions were separable from each other on an immunoadsorbent prepared from rabbit collagen. One reacted exclusively with carp collagen, the other reacted additionally with various mammalian collagens including that from rabbit. The results were interpreted as evidence for the presence of at least two different antigenic determinants on carp collagen resembling former results for calf collagen.
在兔抗酸溶性鲤鱼胶原蛋白血清中,通过被动血凝反应证明存在两种特异性不同的抗体组分。这些抗体组分可在由兔胶原蛋白制备的免疫吸附剂上彼此分离。一种仅与鲤鱼胶原蛋白反应,另一种还与包括兔胶原蛋白在内的各种哺乳动物胶原蛋白反应。这些结果被解释为鲤鱼胶原蛋白上至少存在两种不同抗原决定簇的证据,这与小牛胶原蛋白的先前结果相似。