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[通过改变钙离子浓度对兔心房肌钙诱导钾电导进行定量描述]

[Quantitative description of a calcium induced potassium conductance of the rabbit atrial myocardium by variation of the Ca++ concentration].

作者信息

Nilius B

出版信息

Acta Biol Med Ger. 1979;38(7):999-1005.

PMID:543377
Abstract

Action potentials of trabeculae from the left rabbit atrium were studied using a modified sucrose gap method. A mathematical treatment of the action potential time course and the phase plane trajectories gives an approximation of a potassium conductance of gK.GK increases be action potential shows a maximum at 1 s.gK reaches a steady state level after 40 s. The experimental findings are interpreted by means a mathematical model of a Ca++-induced K+-conductance.

摘要

采用改良的蔗糖间隙法研究了兔左心房小梁的动作电位。对动作电位时程和相平面轨迹进行数学处理,得出钾电导gK的近似值。gK随动作电位增加,在1秒时达到最大值。40秒后gK达到稳态水平。通过钙诱导钾电导的数学模型对实验结果进行了解释。

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