Nilius B, Boldt W
Acta Biol Med Ger. 1979;38(8):1175-82.
Cs+ (15-20 mM) decreases the electrotropic vagal effects on an isolated vagal innervated rabbit atrium. By means of investigating the action potentials and the phase plane trajectories of trabeculae from the rabbit atrium using a modified single sucrose gap technique the anomalous rectification disappears and also the effect of acetylcholine (ACh) on action potential duration. We presume that the anomalous rectification should be a necessary condition of electrotropic vagal (ACh) action on the rabbit atrium.
15 - 20毫摩尔的铯离子可降低电刺激对离体迷走神经支配的兔心房的迷走神经效应。通过使用改良的单蔗糖间隙技术研究兔心房小梁的动作电位和相平面轨迹,反常整流消失,乙酰胆碱(ACh)对动作电位持续时间的影响也消失。我们推测,反常整流应该是电刺激迷走神经(ACh)作用于兔心房的必要条件。