Spector S, Parker C W
Science. 1970 Jun 12;168(3937):1347-8. doi: 10.1126/science.168.3937.1347.
The development of a radioimmunoassay for morphine is described. The hapten morphine is made antigenic by coupling it to a protein at the phenolic group of the molecule. Extremely low concentrations of morphine (0.5 nanogram) can be measured by this assay procedure.
本文描述了一种吗啡放射免疫测定法的开发。半抗原吗啡通过在分子的酚基团处与蛋白质偶联而具有抗原性。通过该测定程序可以检测到极低浓度的吗啡（0.5纳克）。
