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贫血女性心理运动功能铁疗法的临床试验

Clinical trial of iron therapy of psychomotor function in anaemic women.

作者信息

Elwood P C, Hughes D

出版信息

Br Med J. 1970 Aug 1;3(5717):254-5. doi: 10.1136/bmj.3.5717.254.

Abstract

A variety of aspects of psychomotor function were assessed in 47 women before and after iron therapy. These women, all of whom had initial haemoglobin levels below 10.5 g./100 ml., had been drawn from a population sample of 2,283 women seen at a haematological screening survey. There was no evidence of any beneficial effect of a rise in haemoglobin level on psychomotor function or on symptoms. Possibly this is because if an effect does occur it is unlikely to be apparent unless the haemoglobin level is very low. If this is true then anaemia is probably a rare cause of symptoms or impairment in psychomotor function in the community.

摘要

在47名女性接受铁剂治疗前后,对她们的多种精神运动功能方面进行了评估。这些女性的初始血红蛋白水平均低于10.5克/100毫升,她们是从2283名接受血液学筛查的女性人群样本中抽取的。没有证据表明血红蛋白水平升高对精神运动功能或症状有任何有益影响。可能是因为即使确实存在某种影响,除非血红蛋白水平非常低,否则这种影响不太可能显现出来。如果这是真的,那么在社区中,贫血可能是导致症状或精神运动功能受损的罕见原因。

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本文引用的文献

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Iron-containing enzymes in the buccal epithelium.口腔上皮中的含铁酶。
Lancet. 1961 Dec 16;2(7216):1331-3. doi: 10.1016/s0140-6736(61)90903-5.
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Effect of oral iron therapy on the symptoms of anaemia.口服铁剂治疗对贫血症状的影响。
Br J Prev Soc Med. 1966 Oct;20(4):172-5. doi: 10.1136/jech.20.4.172.
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