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全科医疗中的地高辛测定

Digoxin measurements in general practice.

作者信息

Holt D W, Williamson J D, Volans G N

出版信息

Br J Clin Pharmacol. 1977 Jun;4(3):321-6. doi: 10.1111/j.1365-2125.1977.tb00720.x.

Abstract

1 As part of a prospective study on the use of digoxin in a general practice, plasma digoxin concentrations were measured in all patients receiving the drug. 2 A low mean plasma digoxin concentration was observed, suggesting a cautious approach to digitalization. 3 The correlation between plasma digoxin concentration and signs or symptoms commonly used in the assessment of digoxin effect was poor. 4 It was concluded that the measurement of plasma digoxin could be of assistance in a variety of clinical settings within a general practice.

摘要
  1. 作为一项关于地高辛在普通医疗实践中使用情况的前瞻性研究的一部分,对所有接受该药物治疗的患者进行了血浆地高辛浓度测定。

  2. 观察到平均血浆地高辛浓度较低,这表明在洋地黄化过程中应谨慎行事。

  3. 血浆地高辛浓度与常用于评估地高辛疗效的体征或症状之间的相关性较差。

  4. 得出的结论是,血浆地高辛测定在普通医疗实践的各种临床环境中可能会有所帮助。

相似文献

1
Digoxin measurements in general practice.全科医疗中的地高辛测定
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Discontinuation of maintenance digoxin therapy in general practice.
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The influence of kidney function, body size and age on plasma concentration and urinary excretion of digoxin.
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本文引用的文献

1
Digitalis intoxication: a clinical report of 148 cases.洋地黄中毒:148例临床报告
Ann Intern Med. 1959 Apr;50(4):869-78. doi: 10.7326/0003-4819-50-4-869.
5
Maintenance digoxin in elderly patients.老年患者地高辛的维持治疗
Br Med J. 1970 Jun 20;2(5711):705-6. doi: 10.1136/bmj.2.5711.705.
8
Digoxin metabolism in obesity.肥胖状态下的地高辛代谢
Circulation. 1971 Nov;44(5):810-4. doi: 10.1161/01.cir.44.5.810.

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