Holt D W, Williamson J D, Volans G N
Br J Clin Pharmacol. 1977 Jun;4(3):321-6. doi: 10.1111/j.1365-2125.1977.tb00720.x.
1 As part of a prospective study on the use of digoxin in a general practice, plasma digoxin concentrations were measured in all patients receiving the drug. 2 A low mean plasma digoxin concentration was observed, suggesting a cautious approach to digitalization. 3 The correlation between plasma digoxin concentration and signs or symptoms commonly used in the assessment of digoxin effect was poor. 4 It was concluded that the measurement of plasma digoxin could be of assistance in a variety of clinical settings within a general practice.
作为一项关于地高辛在普通医疗实践中使用情况的前瞻性研究的一部分，对所有接受该药物治疗的患者进行了血浆地高辛浓度测定。
观察到平均血浆地高辛浓度较低，这表明在洋地黄化过程中应谨慎行事。
血浆地高辛浓度与常用于评估地高辛疗效的体征或症状之间的相关性较差。
得出的结论是，血浆地高辛测定在普通医疗实践的各种临床环境中可能会有所帮助。
