Prier A, Camus J P, Guillemant S, Grumbach R, Kremer R
Rev Rhum Mal Osteoartic. 1979 Oct;46(10):517-21.
Dosages of 25 (OH) D and of 24, 25 (OH) 2 D in the plasma were done in March and October in 26 women more than 70 years old, hospitalized in a semi-chronic disease hospital of the Paris area. Eleven young adults, studied in June, served as control. There was a significant decrease of 25 (OH) D and 24,25 (OH) 2 D in older individuals (pL 0,001). In march, the levels of 25 (OH) D and 24,25 (OH) 2 D were respectively 2,7 +/- 1,6 mg/ml and 0,88 +/- 0,53 mg/ml. In October the level of 25 (OH) D (5,8 +/- 2,6 mg/ml) were significantly higher (p L 0,01) whereas the level of 24,25 (OH) 2 D did not vary (0,84 +/- 0,58 mg/ml). These results are in agreement with those obtained in England. The underline the relative deficit vitamin D in older individuals. The constant decrease of 24, 25 (OH) 2 D remained unexplained.
对巴黎地区一家半慢性病医院收治的26名70岁以上女性，于3月和10月检测了她们血浆中25（OH）D和24,25（OH）₂D的含量。6月研究的11名年轻人作为对照。老年人的25（OH）D和24,25（OH）₂D显著降低（p＜0.001）。3月时，25（OH）D和24,25（OH）₂D的水平分别为2.7±1.6毫克/毫升和0.88±0.53毫克/毫升。10月时，25（OH）D的水平（5.8±2.6毫克/毫升）显著更高（p＜0.01），而24,25（OH）₂D的水平没有变化（0.84±0.58毫克/毫升）。这些结果与在英国获得的结果一致。它们强调了老年人中维生素D的相对缺乏。24,25（OH）₂D持续降低的原因仍无法解释。
