Malmberg H, Holopainen E
Allergy. 1979 Oct;34(5):331-7. doi: 10.1111/j.1398-9995.1979.tb04375.x.
From a previous sample of 634 students and school children, 115 subjects were selected for a thorough rhinological examination and allergy work-up in order to assess the value of nasal secretion eosinophilia in screening for immediate-type nasal allergy. Part of the subjects had, in the previous study, been found to have secretion eosinophilia and a history of chronic/allergic rhinitis, part of the subjects had either a secretion eosinophilia or a rhinitis history, and part of them had neither a secretion eosinophilia nor a rhinitis history. A significant correlation was obtained between secretion eosinophilia and allergy. Nasal provocation tests correlated with skin tests in 87%, whereas the correlation between nasal provocation tests and Ige determinations in the serum was poorer. Thickening of the maxillary sinus was, when present, usually attributable to infection and not to allergy. Reasons for "false positive or false negative" smears for eosinophils are discussed.
从之前634名学生和学龄儿童的样本中，选取了115名受试者进行全面的鼻科检查和过敏评估，以评估鼻分泌物嗜酸性粒细胞增多在速发型鼻过敏筛查中的价值。在之前的研究中，部分受试者被发现有分泌物嗜酸性粒细胞增多及慢性/过敏性鼻炎病史，部分受试者有分泌物嗜酸性粒细胞增多或鼻炎病史，还有部分受试者既无分泌物嗜酸性粒细胞增多也无鼻炎病史。分泌物嗜酸性粒细胞增多与过敏之间存在显著相关性。鼻激发试验与皮肤试验的相关性为87%，而鼻激发试验与血清中IgE测定的相关性较差。上颌窦增厚（若存在）通常归因于感染而非过敏。文中讨论了嗜酸性粒细胞涂片出现“假阳性或假阴性”的原因。
