Gray P S, Hunter R, Patterson R M
Cytobios. 1979;25(99-100):175-82.
Azo dyes have been shown to be mutagenic and toxic in a variety of organisms. The azo dye, Dispersion Yellow 3 is a pollutant in the river water supply of Northern Georgia. Preliminary and definitive studies have indicated that it is mutagenic in micro-organisms and causes several malformations in chicken embryos. The present study revealed that when larvae are exposed to the dye during tail regeneration, several aberrations are seen in the squash preparations from regenerates. Included are gaps (the most frequent abnormality), dicentrics, rings and breaks. The data suggest that this azo dye deserves more detailed study to determine its mutagenicity.
偶氮染料已被证明在多种生物体中具有致突变性和毒性。偶氮染料分散黄3是佐治亚州北部河流水源中的一种污染物。初步和确定性研究表明，它在微生物中具有致突变性，并会导致鸡胚胎出现多种畸形。本研究表明，当幼虫在尾巴再生期间接触该染料时，在再生组织的压片标本中会出现几种畸变。包括裂隙（最常见的异常）、双着丝粒体、环状染色体和断裂。数据表明，这种偶氮染料值得进行更详细的研究以确定其致突变性。
