肝脏疾病中的“干燥综合征”。
"Sicca complex" in liver disease.
作者信息
Golding P L, Bown R, Mason A M, Taylor E
出版信息
Br Med J. 1970 Nov 7;4(5731):340-2. doi: 10.1136/bmj.4.5731.340.
Abstract
Sixty-three patients with liver disease were studied for the presence of the components of Sjögren's syndrome. The "sicca complex" (that is, patients without arthritis) was detected in 42% of patients with active chronic hepatitis, 72% with primary biliary cirrhosis, and 38% with cryptogenic cirrhosis. One patient with active chronic hepatitis and one with primary biliary cirrhosis had rheumatoid arthritis. No evidence of Sjögren's syndrome was detected in seven patients with alcoholic cirrhosis. It is suggested that the sicca complex and autoimmune liver disease may be part of a systemic disorder in which immunological mechanisms are concerned in the pathogenesis.
摘要
对63例肝病患者进行了干燥综合征成分的研究。在42%的活动性慢性肝炎患者、72%的原发性胆汁性肝硬化患者和38%的隐源性肝硬化患者中检测到了“干燥综合征”（即无关节炎的患者）。1例活动性慢性肝炎患者和1例原发性胆汁性肝硬化患者患有类风湿性关节炎。7例酒精性肝硬化患者未检测到干燥综合征的证据。提示干燥综合征和自身免疫性肝病可能是一种系统性疾病的一部分，其中免疫机制参与了发病过程。
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