Stöhr J, Gürtler H, Brenner K V, Ellrich T
Arch Exp Veterinarmed. 1979;33(5):725-43.
Single glucose doses of 0.5 g/kg body weight or 1.0 g/kg were intravenously applied at ambient temperatures between 25 degrees C and 30 degrees C pigs aged between zero and 20 hours two and three, five and seven, ten and 14, 20 and 30 days, and eight weeks. With reference to excess glucose curves in the blood and plasma, the half-life of glucose elimination was graphically determined in a semi-logarithmic system. The result obtained was used to calculate the coefficients of assimilation and distribution, as well as the readily exchangeable pool and the transfer rate of glucose. On the average the half-life of glucose elimination in the five groups of the piglets was identical (0.47 hour); in contrast it was faster in weaners (0.17 hour) than in piglets. With reference to the plasma values, the volume of the glucose distribution decreased continuously with growing age. Average glucose transfer amounted to 1.02 mg/g. hr in weaners and thus was twice as much as that recorded for the five groups of the piglets. Reduction of ambient temperatures between 15 degrees C and 18 degrees C had no bearing on the parameters of 30-day piglets. These findings are likely to suggest that there is no increased glucose turnover within the thermal neutral zone in piglets over the first days of age and, consequently, cannot contribute to the development of hypoglycaemia.
在环境温度为25摄氏度至30摄氏度的条件下，给年龄在0至20小时、2至3天、5至7天、10至14天、20至30天以及8周的仔猪静脉注射单剂量为0.5克/千克体重或1.0克/千克体重的葡萄糖。参照血液和血浆中的过量葡萄糖曲线，在半对数系统中通过图表确定葡萄糖消除的半衰期。所得结果用于计算同化和分布系数，以及葡萄糖的易交换池和转移速率。平均而言，五组仔猪的葡萄糖消除半衰期相同（0.47小时）；相比之下，断奶仔猪的半衰期更快（0.17小时）。就血浆值而言，葡萄糖分布体积随着年龄增长而持续下降。断奶仔猪的平均葡萄糖转移量为1.02毫克/克·小时，因此是五组仔猪记录值的两倍。将环境温度降至15摄氏度至18摄氏度对30日龄仔猪的参数没有影响。这些发现可能表明，在仔猪出生后的头几天，在热中性区内葡萄糖周转率没有增加，因此不会导致低血糖症的发生。
