O'Malley C B, Ward J D, Timperley W R, Porter N R, Preston F E
Lancet. 1975 Dec 27;2(7948):1274-6. doi: 10.1016/s0140-6736(75)90610-8.
Abnormal platelet function has been demonstrated in 20 patients with diabetic peripheral neuropathy. The results are compared to those obtained from 19 matched diabetic patients with no clinical evidence of complications and 20 matched normal control subjects. Platelets from patients with diabetic neuropathy showed an increased sensitivity to the aggregating agents adenosine diphosphate and adrenaline. Spontaneous platelet aggregation was demonstrated in both groups of diabetic patients.
在20例糖尿病周围神经病变患者中已证实存在血小板功能异常。将这些结果与19例无并发症临床证据的匹配糖尿病患者以及20例匹配的正常对照受试者所获得的结果进行比较。糖尿病神经病变患者的血小板对聚集剂二磷酸腺苷和肾上腺素表现出更高的敏感性。两组糖尿病患者均出现了自发性血小板聚集。
