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来自一家蠕形螨病高发犬舍的健康幼犬对PHA-P的皮肤反应不足。

Deficient cutaneous response to PHA-P in healthy puppies from a kennel with a high prevalence of demodicosis.

作者信息

Wilkie B N, Markham R J, Hazlett C

出版信息

Can J Comp Med. 1979 Oct;43(4):415-9.

Abstract

Intradermal injection of phytohemagglutinin was used to evaluate the integrity of cell-mediated immunological reactions in Doberman puppies thought to be predisposed to demodicosis. Results indicate a statistically significant deficiency of cutaneous delayed response in these dogs when compared with age matched Beagles, adult Dobermans or random control dogs of various ages and breeding. The high prevalence of demodicosis in the kennel of origin may have been due to the observed deficiency of cutaneous immune function.

摘要

采用皮内注射植物血凝素的方法,评估被认为易患蠕形螨病的杜宾幼犬细胞介导免疫反应的完整性。结果表明,与年龄匹配的比格犬、成年杜宾犬或不同年龄和品种的随机对照犬相比,这些犬的皮肤迟发性反应在统计学上存在显著不足。原犬舍中蠕形螨病的高发病率可能是由于观察到的皮肤免疫功能缺陷所致。

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本文引用的文献

2
Phytohemagglutinin skin test: a possible in vivo measure of cell-mediated immunity.
J Pediatr. 1972 Oct;81(4):775-80. doi: 10.1016/s0022-3476(72)80101-x.
3
Phytohemagglutinin (PHA) skin test in the diagnosis of cellular immunodeficiency.
J Allergy Clin Immunol. 1973 Jul;52(1):31-7. doi: 10.1016/0091-6749(73)90118-8.
9
Immunobiology of aging: evaluation of current status.衰老的免疫生物学:现状评估
Clin Immunol Immunopathol. 1976 Nov;6(3):394-413. doi: 10.1016/0090-1229(76)90093-3.

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