Bjure J, Grimby G, Kasalický J, Lindh M, Nachemson A
Thorax. 1970 Jul;25(4):451-6. doi: 10.1136/thx.25.4.451.
Fifty patients aged 11 to 78 years with untreated idiopathic scoliosis were studied. An increased frequency of respiratory impairment was found, especially in patients with a severe degree of scoliosis. Seven patients under 60 years were unable to work and all had thoracic curves exceeding 100°. None of the patients between 20 and 65 years of age was engaged in hard work and 22% had a disability pension, all because of respiratory impairment. A tendency to increased shortness of breath was noted with increasing curves as well as age. Dynamic and static spirometry was performed and airway closure was studied with the xenon-133 bolus technique. With increasing degrees of scoliosis there was a reduction in all lung volumes. Seventeen of 40 patients showed evidence of airway closure at lung volumes greater than functional residual capacity; 6 of these patients were under 40 years of age, and all had thoracic scoliosis exceeding 90°.
对50例年龄在11至78岁之间未经治疗的特发性脊柱侧凸患者进行了研究。发现呼吸功能损害的发生率增加，尤其是在重度脊柱侧凸患者中。7名60岁以下的患者无法工作，所有患者的胸弯均超过100°。20至65岁的患者中没有人从事繁重工作，22%的患者领取残疾抚恤金，均是因为呼吸功能损害。随着侧弯程度和年龄的增加，呼吸急促的趋势更加明显。进行了动态和静态肺量测定，并采用氙-133团注技术研究了气道闭合情况。随着脊柱侧凸程度的增加，所有肺容量均减少。40例患者中有17例在肺容量大于功能残气量时出现气道闭合的证据；其中6例患者年龄在40岁以下，均有超过90°的胸段脊柱侧凸。
