Jones R S, Kennedy J D, Hasham F, Owen R, Taylor J F
Thorax. 1981 Jun;36(6):456-61. doi: 10.1136/thx.36.6.456.
The mechanism of impairment of ventilatory function in idiopathic scoliosis has been studied in 23 children, all girls, and compared with 27 normal children and 24 normal young adult females. The vital capacity, FEV 1, gas transfer factor, and the maximum static expiratory airway pressure were all significantly reduced. total lung capacity and the maximum inspiratory pressure were lower than in the normal subjects, but the difference was not significant. Restriction of thoracic cage movement by a belt showed that the thorax in the children with scoliosis was as mobile as in the normal subjects. The results are explained in terms of the characteristic deformity in scoliosis which causes one hemi-thorax to become relatively smaller than the other. It is concluded that this causes an inherent mechanical inefficiency of ventilation which is likely to contribute to respiratory failure in these subjects.
对23名儿童（均为女孩）特发性脊柱侧弯通气功能损害的机制进行了研究，并与27名正常儿童和24名正常年轻成年女性进行了比较。肺活量、第一秒用力呼气容积、气体交换因子和最大静态呼气气道压力均显著降低。肺总量和最大吸气压力低于正常受试者，但差异不显著。用束带限制胸廓活动表明，脊柱侧弯儿童的胸廓活动度与正常受试者相同。结果根据脊柱侧弯的特征性畸形来解释，这种畸形导致一侧半胸廓比另一侧相对变小。得出的结论是，这会导致通气的内在机械效率低下，这可能是这些受试者呼吸衰竭的原因。
