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头孢克洛治疗慢性支气管炎急性加重期。

Cefaclor therapy in acute exacerbations of chronic bronchitis.

作者信息

Wernstedt L, Berntsson E, Thiringer G

出版信息

Postgrad Med J. 1979;55 Suppl 4:56-8.

PMID:548943
Abstract

Twenty-four patients with acute exacerbations of chronic bronchitis were treated with cefaclor at a dose of 500 mg every 8 hours for 10 days. Studies included volume, appearance and bacteriological examination of sputum, and haematological and virus serology tests. The response to therapy was judged on the reduction in sputum volume or the conversion of its character from purulent to mucoid. Nineteen of 24 patients improved and in 4 of 5 failures, positive serology for influenza virus was found. Growth of Pseudomonas occurred in one sputum. Minor side effects were seen in 3 patients, and no haematological or biochemical abnormalities were found.

摘要

24例慢性支气管炎急性加重患者接受头孢克洛治疗,剂量为500毫克,每8小时一次,共10天。研究包括痰液的量、外观和细菌学检查,以及血液学和病毒血清学检测。根据痰液量的减少或其性质从脓性转变为黏液性来判断治疗反应。24例患者中有19例病情改善,5例治疗失败的患者中有4例流感病毒血清学检测呈阳性。一份痰液样本中出现了铜绿假单胞菌生长。3例患者出现轻微副作用,未发现血液学或生化异常。

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